The foundation of the University of Guanajuato goes back to the year 1732. Since then, the university adopted several names, until March 1945, when the rank of University was acquired as well as the name for which is now known.

With a population of nearly 34,000 students, today, the University of Guanajuato is present in 12 cities within the entity through four campuses and one high school college with ten high schools.